SupplementaryTable_5.7.xlsx

Table 5.7. Significant SNPs from pairwise CPASSOC SHet tests. SNPs are represented in the table if they satisfied the following conditions: 1) The SNP demonstrated genome-wide significance in its CPASSOC SHet test (5x10-8), and 2) the SNP demonstrated a p-value<0.005 in both individual GWAS contributing to the pairwise test. p-values formatted to Scientific notation in Excel and Beta values formatted to three decimal place (Number) in Excel. SNP, rsID identification for single nucleotide polymorphisms; CHR, chromosome; A1 (Effect), effect allele; A2, non-effect allele; Overlapped Gene (if applicable), variants which were identified as protein-coding have their overlapped gene listed where applicable; P_SHet, p-value determined SHet test with CPASSOC (Zhu et al., 2015); Trait_P, p-value associated with Brown hair, Skin colour or Tanning ability; Trait_B, beta (effect size and direction) associated with Brown hair, Skin colour or Tanning ability from individual GWAS; PD_P, p-value associated with PD from individual GWAS; PD_B, beta (effect size and direction) associated with PD from individual GWAS; P_Shet, test statistic that is an extension of SHom, but maintains statistical power when heterogeneity exists.