Comparative gene expression profiling of mouse pXEN, XEN, ES, and rat XENP cells

We derived and describe a novel mouse cell type that we name primitive XEN (pXEN) cells, and compare their gene expression profiles with other stem cell types previously derived from rodent blastocysts. Overall design: Each cell type was cultured in its respective maintenance condition. Samples were collected after 2 days of culture. Each sample corresponds to an independently derived cell line: Mouse pXEN cells, 3 samples; mouse XEN cells, 3 samples; rat XENP cells, 4 samples; mouse ES cells, 2 samples.