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Supplementary Table S3 from DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia

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Figshare2016-05-01 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Supplementary_Table_S3_from_DNMT3A_Haploinsufficiency_Transforms_i_FLT3_i_sup_ITD_sup_Myeloproliferative_Disease_into_a_Rapid_Spontaneous_and_Fully_Penetrant_Acute_Myeloid_Leukemia/22531112
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Differentially methylated regions (DMR) in human FLT3-ITD/DNMT3A-mut versus FLT3-ITD/DNMT3A-wt AML and in murine Flt3ITD/ITD;Dnmt3afl/fl MxCre AML versus Flt3ITD/ITD;Dnmt3afl/fl MPN control mice. Lists of AML-unique and HSPC-like DMR associated genes in human and mouse based on DMRs found only in the Dnmt3a mutant AML groups or DMRs in Dnmt3a mutant AML with similar methylation patterns to normal HSC.
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2016-05-01
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