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Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an inhibitor

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Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an inhibitor Descriptor: 1,2-ETHANEDIOL, 5-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)pentyl (2~{S},3~{R})-2-azanyl-3-oxidanyl-butanoate, GLYCEROL, ... Authors: Guo, J, Chen, B, Zhou, H. Deposit date: 2020-06-12 Release date: 2020-10-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Structure-guided optimization and mechanistic study of a class of quinazolinone-threonine hybrids as antibacterial ThrRS inhibitors. Eur.J.Med.Chem., 207, 2020
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2020-06-12
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