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Locally-Directed Morphogenesis Enabling Engineered hPSC Embryoids for Robust Symmetry Breaking

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP492886
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Controlling the modality of the morphogen BMP4 controls and alters the gene expression and developmental trajectory within hPSC embryoids. Overall design: Three different modalities of BMP4 (localized, immbolized BMP4 with no BSA, localized, immobilized BMP4 with BSA, and global BMP4 distrubuted in media) were tagged with 3 hashing antibodies (TotalSeq™-B0251,B0252,B0253 anti-human Hashtag 1,2,3) and analyzed using scRNA sequencing using 10X genomics
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2025-03-01
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