Transcriptomic analysis of antigen experienced Mariyln (TCR-transgenic) CD4 T cells proliferation during an ongoing immune response in vivo
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE154793
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资源简介：
The study explore the intrinisic inhibitors of antigen experienced Marilyn CD4 T cells (TCR-Tg) expansion after footpad vaccinations in vivo and in the presence of a first cohort of expanded Marilyn cells to mimick an ongoing immune response C57BL6 mice are intravenously injected with either naive or antigen experienced Marilyn cells and restimulated via footpad vaccinations (DC+peptide) in the presence of the first cohort of Marilyn cells, mimicking an ongoing CD4 immune response. CD4 T cells are sorted from draining lymph node, 7 days after transfer.
创建时间：
2021-09-03
