A base editor facilitates simultaneous purine and pyrimidine substitutions
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP605979
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资源简介:
We have developed the ACGBEmax system, which is created by fusing a dual-functional deaminase, an engineered N-methylpurine DNA glycosylase, and an evolved SRAP domain with nCas9 (D10A). This system enables the precise conversion of A, C, and G to other bases in mammalian cells, thereby generating a wide range of base mutation types.
创建时间:
2025-08-31



