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Type II but not type I interferon signaling is indispensable for TLR7-promoted development of autoreactive B cells and systemic autoimmunity

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141433
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The gene transcripts in splenic tissues derived from imiquimod treated B6.Sle1b and B6.Sle1b.IFNgR-/- mice were analyzed by RNA sequencing. To investigate how IFNg may promote autoreactive B cell development into the AFC and GC pathways in TLR7-accelerated SLE, we analyzed the gene transcripts in spleens of IMQ-treated B6.Sle1b and Sle1b.IFNgR-/- mice by RNA sequencing.
创建时间:
2019-12-06
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