Pleiotropy alleviates the fitness costs associated with resource allocation trade-offs in immune signaling networks

Many genes and signaling pathways within plant and animal taxa drive the expression of multiple organismal traits. This form of genetic pleiotropy instigates trade-offs among life-history traits if a mutation in the pleiotropic gene improves the fitness contribution of one trait at the expense of another. Whether or not pleiotropy gives rise to conflict among traits, however, likely depends on the resource costs and timing of trait deployment during organismal development. To investigate factors that could influence the evolutionary maintenance of pleiotropy in gene networks, we developed an agent-based model of co-evolution between parasites and hosts. Hosts comprise signaling networks that must faithfully complete a developmental program while also defending against parasites, and trait signaling networks could be independent or share a pleiotropic component as they evolved to improve host fitness. We found that hosts with independent developmental and immune networks were significant..., , , # Data from: Pleiotropy alleviates the fitness costs associated with resource allocation trade-offs in immune signaling networks

[https://doi.org/10.5061/dryad.sqv9s4n9f](https://doi.org/10.5061/dryad.sqv9s4n9f)

The file submitted here contains the datasets used to generate the figures in the paper \"Pleiotropy alleviates the fitness costs associated with resource allocation trade-offs in immune signaling networks\". Code used to generate figures using this data is available at [https://github.com/Reese-Martin/Pleiotropy_And_Resource_Allocation](https://github.com/Reese-Martin/Pleiotropy_And_Resource_Allocation)

## Description of the data and file structure

The data is currently in a zip file, expanding this file will show several individual data files that contain population fitness information, host signaling networks, and other associated data.

All data are stored as .jld2 files which can be saved and loaded using the FileIO package in the Juila programming language. each data fil...