Stat5a Core in complex with Compound 12
收藏Protein Data Bank Japan2024-05-22 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7uc6
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Stat5a Core in complex with Compound 12 Descriptor: N-{5-[difluoro(phosphono)methyl]-1-benzothiophene-2-carbonyl}-3-methyl-L-valyl-L-prolyl-N~3~-(4-bromophenyl)-N,N-dimethyl-beta-alaninamide, Signal transducer and activator of transcription 5A Authors: Meagher, J.L, Stuckey, J.A. Deposit date: 2022-03-16 Release date: 2023-02-15 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.101 Å) Cite: Discovery of a Potent and Selective STAT5 PROTAC Degrader with Strong Antitumor Activity In Vivo in Acute Myeloid Leukemia. J.Med.Chem., 66, 2023
创建时间：
2022-03-16
