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Functional Assay Profile of GPER and ERα Activity.

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aActivity determined by the ability of compounds at 1 µM to induce calcium mobilization or of compounds at 10 µM to block calcium mobilization induced by 200 nM 17β-estradiol. bActivity determined by the ability of compounds at 10 µM to induce nuclear translocation of PH-RFP or to block translocation induced by 100 nM 17β-estradiol.

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2012-10-15
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