Tp53bp1

ENCODES a protein that exhibits damaged DNA binding (ortholog); histone reader activity (ortholog); methylated histone binding (ortholog); INVOLVED IN cellular response to X-ray; DNA damage response (ortholog); DNA repair (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH Bloom syndrome (ortholog); Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); FOUND IN chromosome, telomeric region (ortholog); cytoplasm (ortholog); DNA repair complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; atrazine

编码一种表现出损伤DNA结合（同源物）的蛋白质；组蛋白阅读器活性（同源物）；甲基化组蛋白结合（同源物）；参与细胞对X射线的反应；DNA损伤反应（同源物）；DNA修复（同源物）；参与着丝粒毛细血管扩张突变（ATM）信号通路；组蛋白修饰途径；双链断裂修复的非同源末端连接途径；与Bloom综合征（同源物）相关；与乳腺癌（同源物）相关；与结肠癌（同源物）相关；位于染色体端粒区域（同源物）；细胞质（同源物）；DNA修复复合物（同源物）；与2,3,7,8-四氯二苯并-对-二恶英；全反式视黄酸；三嗪相互作用。