Rad5 recruits error-prone DNA polymerases for mutagenic repair of ssDNA gaps on undamaged templates. Gallo et al.
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Gallo et al. explore how cells repair ssDNA that arises from exogenous and endogenous DNA replication stress. They reveal that recruitment of error-prone polymerases to stressed replication forks results in mutagenic repair of ssDNA. These findings point to an expanded role of error-prone polymerases in replicating the eukaryotic genome.
创建时间：
2018-12-11
