Data underlying the publication: Radiofrequency ablation for thyroid nodules (RATED study) - analysis of a learning curve and predictors of success

<em>Context </em>Radiofrequency ablation (RFA) is used as treatment for symptomatic thyroid nodules. However, factors influencing the volume reduction ratio (VRR) at 12 months are not yet fully understood. <em>Objective </em>The primary objective was evaluating the VRR at 12 months after RFA. Secondary objectives were the assessment of a learning curve and factors influencing the VRR at 12 months. <em>Design </em>This is a retrospective Dutch multi-center study. <em>Patients and intervention </em>Patients who underwent RFA for symptomatic thyroid nodules with available ultrasound follow-up were eligible for this study. <em>Main outcome measures </em>Ultrasound based VRR at 12 months and chronologically numbered RFA procedures. All patients’ baseline, ultrasound, treatment, and early follow-up factors were assessed for correlation with VRR at 12 months.

研究背景（Context）：射频消融术（Radiofrequency ablation, RFA）是有症状甲状腺结节的常用治疗手段，但目前尚不明确影响术后12个月体积缩小率（volume reduction ratio, VRR）的各类因素。
研究目的（Objective）：本研究的首要目的为评估甲状腺结节患者接受射频消融术后12个月的体积缩小率；次要目的为分析射频消融操作的学习曲线，并探讨影响术后12个月体积缩小率的相关因素。
研究设计（Design）：本研究为一项回顾性荷兰多中心研究。
患者与干预措施（Patients and intervention）：本研究纳入因有症状甲状腺结节接受射频消融治疗，且具备超声随访资料的患者。
主要结局指标（Main outcome measures）：主要结局指标包括基于超声检测的12个月体积缩小率，以及按时间顺序编号的射频消融操作。本研究评估了所有患者的基线特征、超声影像指标、治疗相关因素及早期随访指标与12个月体积缩小率的相关性。