Overexpression of brain endothelial mucin-type O-glycan biosynthesis promotes brain homeostasis in aged mice
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE268642
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In our study, we find that AAV-mediated brain endothelial B3GNT3 overexpression reduces neuroinflammatory markers and cognitive deficits in aged mice. Here, we perform snRNA-seq to characterize the cellular and molecular changes induced by brain endothelial B3GNT3 overexpression. snRNA-sequencing of pooled cortical and hippocampal tissues from aged mice treated with AAV-EGFP, aged mice treated with AAV-B3GNT3, and young mice treated with AAV-EGFP
创建时间：
2025-04-02
