Genetic subtraction reveals divergent pathways and targets in anxiety-related and anxiety-independent TMD

This repository contains the summary statistics and downstream analysis outputs supporting the manuscript “Genetic subtraction reveals divergent pathways and targets in anxiety-related and anxiety-independent TMD”. The files included in this repository are described as follows: gsub_analytical_loading1.txt – GWAS summary statistics derived from the genetic subtraction (GSUB) analysis representing the anxiety-related genetic component. gsub_analytical_loading2.txt – GWAS summary statistics derived from the genetic subtraction (GSUB) analysis representing the anxiety-independent genetic component. loading1.enloc.gene.out – Gene-level colocalization results generated using ENLOC for loci associated with the anxiety-related genetic component. loading2.enloc.gene.out – Gene-level colocalization results generated using ENLOC for loci associated with the anxiety-independent genetic component. loading1_susie_res.RData – Fine-mapping results obtained using SuSiE for loci contributing to the anxiety-related genetic component. loading2_susie_res.RData – Fine-mapping results obtained using SuSiE for loci contributing to the anxiety-independent genetic component.