Structure of J-PKAc chimera complexed with Aplithianine B
收藏Protein Data Bank Japan2026-02-11 更新2026-04-19 收录
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Structure of J-PKAc chimera complexed with Aplithianine B Descriptor: 6-[(6P)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7,9-dihydro-8H-purin-8-one, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha Authors: Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R. Deposit date: 2022-12-05 Release date: 2023-10-18 Last modified: 2026-02-11 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases. J.Nat.Prod., 86, 2023
创建时间:
2022-12-05



