Generation of Nickel Siloxycarbene Complexes from Acylsilanes for the Catalytic Synthesis of Silyl Enol Ethers

A catalytic
protocol has been developed to access Fischer carbene
nickel complexes using acylsilanes as stable and readily available
precursors. The as-generated Fischer carbene complexes exhibit versatile
reactivity, including cyclopropanation with alkenes, α-C–H
insertion reactions, and two-component C–H addition to norbornene,
which demonstrates the broad utility of the nickel(0)/acylsilane system
for the catalytic applications of Fischer carbene complexes.

本研究开发了一种催化体系，旨在通过使用酰基硅烷作为稳定且易于获取的前体来制备菲舍尔碳烯镍络合物。所制备的菲舍尔碳烯络合物表现出多面性的反应活性，包括与烯烃的环丙烷化反应、α-C-H插入反应以及对诺伯林烯的C-H加成反应，这充分展示了镍(0)/酰基硅烷体系在菲舍尔碳烯络合物催化应用中的广泛实用性。