Genome-wide analysis of CD14+ monocytes from healthy and paired pre-therapy/post-cycle NHL21 patients. Genome-wide analysis of CD14+ monocytes from healthy and paired pre-therapy/post-cycle NHL21 patients

Gene expression level analysis of healthy, pre-therapy and post-cycle 4 NHL21 patients treated with R-CHOP to show the distinct clustering of healthy/post-cycle 4 monocytes versus pre-therapy and to identify the differentially expressed genes under three different conditions. Overall design: Total RNA obtained from FACS sorted CD14+ monocytes isolated from 6 healthy participants and paired pre-therapy/post-cycle 4 monocytes from 6 NHL21 patients and analysed using Illumina Human HT12v4 Bead Array for whole genome expression.