Aurora B phosphorylates hnRNP U/SAF-A to facilitate XIST RNA removal from the inactive X chromosome during mitosis
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
We show that Aurora-B phosphorylates heterogeneous nuclear ribonucleoprotein U (hnRNP U) in the SAP domain to dissociate hnRNP U from chromatin during mitosis. We use RNA-seq to show that hnRNP U associates with hundreds of mRNAs and lncRNAs during interphase and mitosis. Identification of hnRNP U-enriched RNAs using immunoprecipitation and RNA-seq in retinal pigment epithelium (RPE) cells.
创建时间：
2020-09-02
