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The trappist's approach to pathfinding: elucidating brain wiring using secretory-trap mutagenesis

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PubMed Central2001-08-29 更新2026-05-25 收录
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A key problem in using genetics to dissect the wiring of the mammalian brain lies in discovering which of the billions of neural connections have been disrupted by a particular mutation. A novel gene-trap approach targets the genes involved in brain wiring and labels the axons of neurons expressing those genes, enabling the effects of mutations to be observed directly.

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BMC
创建时间:
2001-08-29
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