Expression data from Sh2b3 Knock-out NOTCH1-induced leukemias. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA188332
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To formally address the tumor suppressor activity of Sh2b3 in vivo, we tested the interaction between oncogenic NOTCH1 and Sh2b3 loss in a retroviral- transduction bone marrow transplantation model of NOTCH-induced T-ALL Forced expression of activated NOTCH1 in this model typically results in full leukemia transformation 5-10 weeks later. Overall design: We performed microarray gene expression analysis of Sh2b3 wild type and Sh2b3–/– NOTCH1 induced leukemias
创建时间：
2013-02-01
