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Sex differences in BACHD activity rhythm parameters.

NIAID Data Ecosystem2026-03-09 收录

亨廷顿病模型

行为节律分析

数据链接：

https://figshare.com/articles/dataset/Sex_differences_in_BACHD_activity_rhythm_parameters_/2293414 数据链接链接失效反馈

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资源简介：

Effects of sex and age on BACHD mouse locomotor activity rhythm parameters (DF = 63).

应用场景：

创建时间：

2016-02-12

干细胞治疗

亨廷顿病模型

Huntington's Disease (HD) is caused by a CAG expansion in the huntingtin gene. Expansion of the polyglutamine tract in the huntingtin protein results in massive cell death in the striatum of HD patien

NIAID Data Ecosystem50

Allelic Series of Huntington's Disease Knock-in Mice Reveals Expression Discorrelates. Mus musculus

亨廷顿病模型

纹状体转录组分析

We report a simultaneous comparison of striatal mRNA levels by RNA sequencing mice with graded levels of HD-like abnormalities Overall design: Examination of 4 different mouse lines

NIAID Data Ecosystem20

Additional file 1 of Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes

亨廷顿病模型

白细胞介素-6缺乏

Additional file 1: Supplementary materials.

Figshare2020-05-25 更新10

Additional file 4: of Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse

亨廷顿病模型

基因表达验证

Table S4. qPCR validation of striatal gene expression identified in RNAseq and pathway analysis. (XLSX 10 kb)

NIAID Data Ecosystem30

Cortical organoids in Huntington's disease reveal a chaotic premature corticogenesis cascade and precede HD subcortical projections

亨廷顿病模型

皮质类器官基因表达

Bulk RNA-seq characterization of human cortical organoids derived from two HD patients (CAG55 and 59) and one healthy (CAG19) sibling's induced pluripotent stemm cells (iPSCs) and human embryonic ste

NIAID Data Ecosystem10

Sex differences in BACHD activity rhythm parameters.

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