Metadata record for the manuscript: The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia

Summary This metadata record provides details of the data supporting the claims of the related manuscript: “The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia”. The related study used a glucocorticoid-induced gene signature to develop a deep learning model that can predict dexamethasone sensitivity. Type of data: gene expression data, uncropped western blot, upstream kinase scores, synergy data. Subject of data: cell lines and patients with acute lymphoblastic leukemia Data access The gene expression data are openly available in ArrayExpress at https://identifiers.org/arrayexpress:E-MTAB-9250. The following additional data files underlying Figures 2, 5 and 6, and Supplementary Figures 1 and 7 are openly available in figshare at https://doi.org/10.6084/m9.figshare.13414706: Uncropped_WB_Figure_2d_j.pdf, Uncropped_WB_Figure_5e_f.pdf, Synergy_data.xlsx, Upstream Kinase Score_PTK_Figure_2a.png, Upstream Kinase Score_STK_Figure_2b.png, SUP-B15_EC50.pzf. A detailed spreadsheet of all data underlying the figures and supplementary files in the related manuscript is included with this metadata record in the file ‘Shah_Ahmed_Kazi_data_locations.xlsx’. This includes both data generated during the study and data from other sources used in the study. Corresponding author(s) for this study Julhash U. Kazi, Division of Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon village Building 404:C3, Scheelevägen 8, 22363 Lund, Sweden. Email: [e-mail]. Phone: [phone].