BIOGRID CURATED DATA FOR VID30 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for VID30 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Central component of GID Complex, involved in FBPase degradation; interacts strongly with Gid8p to serve as a scaffold for other GID Complex subunits; contains SPRY domain and 3 domains that are also found in Gid8p - LisH, CTLH, and CRA; required for association of Vid vesicles and actin patches in vacuole import and degradation pathway; shifts the balance of nitrogen metabolism toward glutamate production; localizes to the nucleus and the cytoplasm

针对 VID30（酿酒酵母 S288c）的蛋白质-蛋白质、遗传和化学相互作用数据集，由 BioGRID（https://thebiogrid.org）精心编纂；定义：GID 复合体的核心组分，参与 FBPase 的降解过程；与 Gid8p 强烈相互作用，作为其他 GID 复合体亚基的支架；含有 SPRY 结构域以及亦见于 Gid8p 中的 3 个结构域，即 LisH、CTLH 和 CRA；对于 Vid 胞囊和质膜在溶酶体导入与降解途径中的关联至关重要；调节氮代谢平衡，促进谷氨酸的生成；定位于细胞核和细胞质。