NKp44+ group3 innate lymphoid cells are associated with tumor progression in human colorectal cancer

Innate lymphoid cells (ILCs) are the most recently identified lymphocytes that act as critical mediators of intestinal immune response. ILCs have found to be involved in antitumor or tumor-promoting effects depending on tissues in which they react, but their roles in human colorectal cancer (CRC) have not been explored yet. Overall design: We characterized ILCs in human normal colon and colorectal tumor and investigated whether these cells are implicated in tumor immunity in human CRC.