Quantitative comparative proteomic analysis of ITGB1-knockdown and ITGB1-vector control cells in K562/S

The global proteome analysis by liquid chromatography-mass spectrometry (LC-MS) has emerged as an important tool to study cell signalling. The effect of ITGB1 on imatinib resistance to leukemia was checked by comparing quantitative proteomic analysis of ITGB1-knockdown (ITGB1-KD) and ITGB1- vector control (ITGB1-VC) cells in K562/S.