Gut metabolites predict Clostridioides difficile recurrence

This repository contains:

1. Data used for analyses from:

A) 16S rRNA gene amplicon analysis after paired-end Fastq files were truncated, filtered, denoised, and merged ["1-ASV_Counts.xlsx"]

B) Untargeted metabolomics as provided by Metabolon ["2-UntargetedMetabolomics.xlsx"]

C) Precision SCFA analysis ["3-PrecisionSCFA.xlsx"]

D) Clincal demographic data of the study cohort ["Clinical Demographics.csv"]

2. Detailed results of univariate analyses in sub-folder "Univariate analysis results" for clinical data, untargeted metabolomics data, SCFAs, and ASVs

3. Detailed results of predictive analysis in subfolder "Predictive Analyses results", including per-fold performance results ("9-PredictiveResults.xlsx") and analysis of predictive features for ASVs ("10-ASVsPredictiveAnalysis.xlsx"), untargeted metabolites ("11-MetabsPredictiveAnalysis.xlsx"), targeted SCFAs ("12-SCFAPredictive Analysis.xlsx"), clinical data ("13-DemoPredictiveAnalysis.xlsx") and all data ("14-AllDataPredictiveAnalysis.xlsx")