Whole genome sequencing of six ethnic groups from Burkina Faso, Cameroon, and Tanzania

We conducted low-coverage (~10x) sequencing of six ethnic groups from three malaria-endemic countries in
sub-Saharan Africa, with the aim of characterising genetic diversity and improving imputation performance
for genotyped samples in these populations. This data is part of a pre-publication
release and is available under managed access. Please see https://www.malariagen.net/data/terms-use/human-gwas-data for
more information on MalariaGEN data access policies.

The purpose of the project was to support the discovery and understanding of genetic variants that influence human
disease. Specifically defined goals were:

a. the discovery of single nucleotide variants at frequencies of 1% or higher in diverse populations,
b. even more comprehensive discovery (variants down to frequencies of 0.1 - 0.5%) in functional gene regions, and
c. discovery of structural variants, such as copy number variants, other insertions and deletions, and inversions, including sequence-level understanding of breakpoints.EGA study EGAS00001003648