Expression analysis of hCMEC/D3 PATJ KD cells.. Expression analysis of hCMEC/D3 PATJ KD cells.
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA997244
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资源简介：
Stroke is a leading cause of long-term disability worldwide. Patients with good recovery after ischemic stroke present a higher downregulation of PATJ comparing with patients with marked disability. To understand the effects of PATJ downregulation we generated PATJ-knockdown human microvascular ECs. We used microarrays to detail the gene expression to identify the modulated genes due to the depletion of the PATJ gene. Overall design: To deeper study the molecular events underlying PATJ downregulation in response to ischemic stroke, we generated hCMEC/D3 cell clones stably depleted of PATJ by using lentiviral particles harboring shRNA against PATJ. Three PATJ KD clones were selected for further analysis due to a progressive depletion of the PATJ species
创建时间：
2023-07-21
