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c-MET Y1235D mutant in complex with Tepotinib

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Protein Data Bank Japan2026-03-04 更新2026-04-25 收录
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https://pdbj.org/mine/summary/8aw1
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c-MET Y1235D mutant in complex with Tepotinib Descriptor: 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, Hepatocyte growth factor receptor Authors: Graedler, U, Lammens, A. Deposit date: 2022-08-29 Release date: 2023-09-06 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding. J.Biol.Chem., 299, 2023
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2022-08-29
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