Crystal Structure of the Heterodimeric HIF-2 in Complex with Antagonist Belzutifan
收藏Protein Data Bank Japan2023-11-29 更新2026-04-19 收录
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Crystal Structure of the Heterodimeric HIF-2 in Complex with Antagonist Belzutifan Descriptor: 3-{[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 Authors: Ren, X, Diao, X, Zhuang, J, Wu, D. Deposit date: 2021-12-07 Release date: 2022-09-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.754 Å) Cite: Structural basis for the allosteric inhibition of hypoxia-inducible factor (HIF)-2 by belzutifan. Mol.Pharmacol., 2022
创建时间：
2021-12-07
