IL7R in complex with an antagonist
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IL7R in complex with an antagonist
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创建时间：
2024-11-13
相关数据集
IL7R in complex with an antagonist
IL7R in complex with an antagonist Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ... Authors: Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N. Deposit date: 2021-05-31
Protein Data Bank Japan2024-11-13 更新20
IL7 binds IL7R:JAK1
Interleukin-7 receptor alpha chain (IL7R) binds interleukin-7 (IL7), forming a stable 1:1 IL7:IL7R complex, with a dissociation constant (Kd) of approximately 200 pM (Goodwin et al. 1990, Park et al.
reactome.org40
JAK1 binds IL7R
Interleukin-7 receptor (IL7R) has a small juxta-membrane region known as the Box1 motif, which is conserved throughout the type 1 cytokine receptor family (Murakami et al. 1991) and believed to be the
reactome.org30
Il7r
ENCODES a protein that exhibits cytokine receptor activity (ortholog); interleukin-7 receptor activity (ortholog); INVOLVED IN B cell homeostasis (ortholog); B cell proliferation (ortholog); cell morp
rgd.mcw.edu50
IL7R is phosphorylated on Y499
Interleukin-7 (IL7) signaling is believed to resemble that of other gammaC family receptors, based on detailed studies of the Interleukin-2 receptor. Extending this model to IL7 suggested a series of
reactome.org80
