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Inhibitory activities of MMV Pathogen Box compounds against O2 consumption rate in T. gondii and P. falciparum.

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Figshare2023-07-20 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Inhibitory_activities_of_MMV_Pathogen_Box_compounds_against_O_sub_2_sub_consumption_rate_in_i_T_i_i_gondii_i_and_i_P_i_i_falciparum_i_/23720829
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Determination of the O2 consumption rate (OCR) inhibitory properties of the identified compounds on (A) WT RH strain T. gondii parasites, and on (B) WT 3D7 strain P. falciparum parasites, using a Seahorse XFe96 flux analyzer. T. gondii experiments were conducted on intact parasites, and P. falciparum experiments measured malate-dependent OCR in digitonin-permeabilized parasites. Data are reported as average EC50 value against OCR (EC50OCR) (μM) ± SEM from three or more independent experiments. ND = not determined.
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2023-07-20
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