Analysis of gene expression in orbital tissue in thyroid-associated eye disease

In this study, next-generation transcriptome sequencing technology and bioinformatics analysis were used to identify differentially expressed genes and signaling pathways associated with orbital adipogenesis and muscle fiber formation in thyroid-associated ophthalmopathy (TAO). Overall design: Orbital adipose connective tissues from three cases each in the TAO and control groups were subjected to transcriptome sequencing