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Detection of Differential Proteomes of Human β-Cells During Islet-Like Differentiation Using iTRAQ Labeling

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Detection_of_Differential_Proteomes_of_Human_Cells_During_Islet_Like_Differentiation_Using_iTRAQ_Labeling/2873509
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资源简介:
A human β-cell line, RNAKT-15, was recently established from human pancreatic islets, whereby its differentiation into islet-like β-cells (islet-like RNAKT-15) increased its expression of insulin 2-fold compared with RNAKT-15 cells. To characterize the differentiation of RNAKT-15 cells into islet-like RNAKT-15, microarray and quantitative proteomics were performed. Our analysis of differential proteomic and mRNA expression has resulted in a greater understanding of the molecular functions that are involved in β-cell differentiation and insulin synthesis and release.
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2016-02-26
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