The in vitro influence of adiponectin on the porcine myometrium on days 15 to 16 of gestation.

Adiponectin is secreted by the white adipose tissue and is one of the most important hormones that regulate metabolic homeostasis. The expression of adiponectin and adiponectin receptor genes and proteins in reproductive organs, such as the testes, ovaries and uterus, suggests that adiponectin is also involved in the regulation of reproductive functions. The aim of this study was to explore the influence of adiponectin on global gene expression in the porcine endometrium during early gestation, on days 15 to 16 of pregnancy (implantation period). We analized samples obtained from 4 indyviduals (n=4). Obtained from the uterine horns tissue explants were divided for two groups: controls [without treatment] and adiponectin treated grous. The concentration of adiponectin in the culture medium was 10 µg/ml. In vitro tissue cultures were cultivated with treatments for 24 hours.