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Crystal structure of the human METTL3-METTL14 complex with compound UOZ094

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Protein Data Bank Japan2024-11-13 更新2026-03-28 收录
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Crystal structure of the human METTL3-METTL14 complex with compound UOZ094 Descriptor: (3~{R})-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]-3-[[[6-[[(3~{S})-3-propan-2-yl-2-azoniaspiro[3.3]heptan-2-yl]methyl]naphthalen-1-yl]amino]methyl]piperidin-3-ol, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... Authors: Bedi, R.K, Huang, D, Caflisch, A. Deposit date: 2021-06-03 Release date: 2021-10-20 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
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2021-06-03
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