Effect of depletion of OASIS on gene expression in primary cultured mouse astrocytes during DNA damage response.. Effect of depletion of OASIS on gene expression in primary cultured mouse astrocytes during DNA damage response.

To investigate the roles of OASIS/CREB3L1 in astrocytes during DNA damage response, we established OASIS wild type and deficient primary cultured mouse astrocytes treated with or without anti-cancer drug doxorubicin. We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for OASIS wild type and deficient primary cultured mouse astrocytes and the cells treated with doxorubicin.