Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 21
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https://pdbj.org/mine/summary/5c83
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Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 21 Descriptor: (2R,5R)-4-[2-(6-benzyl-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-1-yl)-2-oxoethyl]-5-(methoxymethyl)-2-methylpiperazin-1-ium, E3 ubiquitin-protein ligase XIAP, ZINC ION Authors: Chessari, G, Buck, I.M, Day, J.E.H, Day, P.J, Iqbal, A, Johnson, C.N, Lewis, E.J, Martins, V, Miller, D, Reader, M, Rees, D.C, Rich, S.J, Tamanini, E, Vitorino, M, Ward, G.A, Williams, P.A, Williams, G, Wilsher, N.E, Woolford, A.J.-A. Deposit date: 2015-06-25 Release date: 2015-08-12 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP. J.Med.Chem., 58, 2015
创建时间：
2015-06-25
