Crystal structure of SARS-CoV-2 NSP14 in complex with compound 1
收藏Protein Data Bank Japan2026-06-17 更新2026-06-30 收录
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Crystal structure of SARS-CoV-2 NSP14 in complex with compound 1 Descriptor: (2~{R},3~{R},4~{S},5~{S})-2-(6-aminopurin-9-yl)-5-(1,3-benzothiazol-2-ylsulfanylmethyl)oxolane-3,4-diol, Guanine-N7 methyltransferase nsp14, IMIDAZOLE, ... Authors: Georgiou, I, Robinson, C, OByrne, S, Matsuda, A, Grygier, P, Smith, C, ONeill, S, Ahmad, S, Post, J, Groenewold, G.J.M, Urakova, N, Wanningen, P, Kresik, L, Plewka, J, Delpal, A, See, K, Eadsforth, T, Paul, M, Lis, K, Decroly, E, Singh Saikatendu, K, Chang, E, Snijder, E.J, Czarna, A, Pyrc, K, Scott, D, Gilbert, I. Deposit date: 2025-07-16 Release date: 2026-01-21 Last modified: 2026-06-17 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase. Rsc Med Chem, 17, 2026
创建时间:
2025-07-16



