RIP1 kinase domain in complex with GDC-8264
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RIP1 kinase domain in complex with GDC-8264 Descriptor: BROMIDE ION, CHLORIDE ION, PROPANE, ... Authors: Lupardus, P, Fong, R, Demircioglu, F.E. Deposit date: 2025-08-15 Release date: 2025-11-12 Last modified: 2025-11-26 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery of Clinical Candidate GDC-8264, a Novel, Potent and Selective RIP1 Inhibitor for Amelioration of Tissue Damage and the Treatment of Inflammatory Diseases. J.Med.Chem., 68, 2025
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2025-08-15



