Immunogenicity (rSBA) of MenPF-1 vaccine in mice (number of doses).

Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined against four target strains using rabbit sera as the complement source. The table shows geometric mean titres, with the 95% confidence intervals of the mean in parentheses. Mice were given 1, 2, 3 or 4 doses of 2.5 μg protein per dose. Note that the data from mice given two doses of 2.5 μg protein per dose is included in Table 2 for comparison, as the immunizations were performed concomitantly.Immunogenicity (rSBA) of MenPF-1 vaccine in mice (number of doses).