Meta-analyses of association of the LCE3C_LCE3B deletion with RA in the Spanish, Chinese and Dutch cohort.

Number of controls in the Spanish, Chinese and Dutch studies is 978, 681 and 779 respectively. The number of controls in the meta-analysis is 2438. LCE3C_LCE3B deletion: deletion of the LCE3B and LCE3C gene; del: deletion; CCP−: patients negative for anti cyclic citrullinated peptide; CCP+: patients positive for anti-cyclic citrullinated peptide; RF−: patients negative for rheumatoid factor; RF+ patients positive for rheumatoid factor. OR: odds ratio; L95: left border 95% confidence interval. R95: right border 95% confidence interval. I2 (p): measure for heterogeneity and p-value of the chi-square test for heterogeneity.