An inhibitor-mediated beta cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP337257
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资源简介：
We have determined that chemical FoxO1 inhibition can effectively mimic many aspects of beta cell dedifferentiation in vitro and that this can be countered by loperamide treatment. Overall design: RNAseq results of murine beta cell line, Min6, treated for 48h with DMSO, AS1842856 (FoxO1 inhibitor), loperamide and in combination.
创建时间：
2021-09-18
