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Control of developmentally primed erythroid genes by combinatorial corepressor actions

ChEBI2015-11-19 更新2026-07-12 收录

血细胞发育基因调控

转录抑制因子组合作用

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-59859 数据链接链接失效反馈

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资源简介：

Control of developmentally primed erythroid genes by combinatorial corepressor actions

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创建时间：

2015-11-19

EBF1转录因子功能

血细胞发育基因调控

To unravel the function of C-terminus domain of EBF1, a replacement microarray analysis was performed by transducing Ebf1wt and Ebf1DC expressing vectors intoA-MuLV transformed pro-B (Ebf1fl/fl;RERTCr

NIAID Data Ecosystem90

Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia

白血病发病机制

血细胞发育基因调控

Glucocorticoids (GCs) are a central component of combination chemotherapy for childhood B-cell precursor acute lymphoblastic leukemia (B-ALL). GCs work by activating the glucocorticoid receptor (GR),

NIAID Data Ecosystem70

Genome-wide occupancy of EBF1-wt & EBF1-H240A. Mus musculus

EBF1转录因子结合位点

血细胞发育基因调控

To study the function of EBF1-H240 residue, genome-wide EBF1 ChIP was performed in A-MuLV transformed pro-B (Ebf1fl/fl;RERTCre) cells transduced with Ebf1wt and Ebf1H240A expressing vectors. Overall d

NIAID Data Ecosystem50

Gene expression and ChIP-seq analysis of hematopoetic progenitors

血细胞发育基因调控

表观遗传学分析

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem80

NKL homeobox gene activities in B-cell development and lymphomas

血细胞发育基因调控

淋巴瘤基因表达

Homeobox genes encode transcription factors which regulate basic processes in development and cell differentiation. Several members of the NKL subclass are deregulated in T-cell progenitors and suppor

NIAID Data Ecosystem50

Control of developmentally primed erythroid genes by combinatorial corepressor actions

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