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Ni–Al Bimetallic Catalyzed Enantioselective Cycloaddition of Cyclopropyl Carboxamide with Alkyne

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Figshare2017-12-07 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Ni_Al_Bimetallic_Catalyzed_Enantioselective_Cycloaddition_of_Cyclopropyl_Carboxamide_with_Alkyne/5681893
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A Ni–Al bimetallic catalyzed enantioselective cycloaddition reaction of cyclopropyl carboxamides with alkynes has been developed. A series of cyclopentenyl carboxamides were obtained in up to 99% yield and 94% ee. The bifunctional-ligand-enabled bimetallic catalysis proved to be an efficient strategy for the C–C bond cleavage of unreactive cyclopropanes.
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2017-12-07
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