Type 1 interferons induce changes in core metabolism that are critical for immune function

ChEBI2016-07-01 更新2026-07-12 收录

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I型干扰素

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-81889 数据链接链接失效反馈

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Type 1 interferons induce changes in core metabolism that are critical for immune function

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2016-07-01

DataSheet_1_Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.zip

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PD-1联合治疗

IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows s

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Immunoediting instructs tumor metabolic reprogramming to support immune evasion [smartseq]

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免疫逃逸机制

Immunoediting sculpts immunogenicity and thwarts host anti-tumor responses in tumor cells during tumorigenesis; however, it remains unknown whether metabolic programming of tumor cells can be guided b

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Lactate Reprograms Glioblastoma Immunity through CBX3-regulated Histone Lactylation [RNA-seq]. Lactate Reprograms Glioblastoma Immunity through CBX3-regulated Histone Lactylation [RNA-seq]

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组蛋白乳酸化

Glioblastoma (GBM), an aggressive brain malignancy with a cellular hierarchy dominated by GBM stem cells (GSCs), evades anti-tumor immunity through mechanisms that remain incompletely understood. Like

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Supplementary Table S2 from Expression of IMPACT Curtails Metabolic Plasticity and Augments NK Cell Killing to Abrogate Metastatic Growth

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NK细胞杀伤机制

Fold change in antioxidant responsive genes upon GCN1 KD in KPC cells grown at physiologic levels of glutamine

Figshare2025-11-03 更新20

Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans.

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B细胞发育

Transcriptional profiling of transitional and follicular B cells showed that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice, characterized by an orchestrated

NIAID Data Ecosystem10

Type 1 interferons induce changes in core metabolism that are critical for immune function

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