Fitted values for exposure to each of the 8 signatures (including the background signature) discovered by applying SparseSignatures to breast cancer data, of each of the 560 whole genomes in the dataset.
Annotated .maf somatic mutation data files for 30 tumour samples from 22 patients Method for somatic mutation calling Somatic single nucleotide variants (SNVs), insertions and deletions (InDel
BackgroundEchinoderm microtubule-associated protein-like 4 (EML4) is the canonical anaplastic lymphoma kinase (ALK) fusion partner in non-small cell lung cancer (NSCLC), and ALK-positive patients show
Summary This metadata record provides details of the data supporting the claims of the related manuscript: “Inflation of Tumor Mutation Burden by Tumor-Only Sequencing in Under-Represented
Sequence data in fastq format was aligned to the GRCh38 reference genome with BWA-MEM and preprocessed with GATK for indel realignment and base quality score recalibration. Aligned sequence was analyz