Transcriptional data from yeast expressing mammalian PIK3CA

We studied the transcriptional profile in response to acute PtdIns-4,5P2 depletion induced by heterologous expression of a plasma membrane-directed version of mammalian PI3K catalytic subunit (p110_-CAAX).本研究针对异源表达质膜靶向型哺乳动物磷脂酰肌醇3-激酶（PI3K）催化亚基（p110_-CAAX）所诱导的急性磷脂酰肌醇-4,5-二磷酸（PtdIns-4,5P2）耗竭，分析了其对应的响应转录谱。